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San Francisco was founded on June 29, 1776, when colonists from Spain established the Presidio of San Francisco at the Golden Gate and Mission San Francisco de Asís a few miles away, both named for Francis of Assisi. San Francisco was ranked 12th in the world and second in the United States on the Global Financial Centres Index as of March 2021. with over 500,000 residents, this CSA had the highest GDP per capita in 2019, at $112,348. Of the 105 primary statistical areas in the U.S. The San Jose–San Francisco–Oakland, CA Combined Statistical Area, with a GDP of $1.09 trillion as of 2019, is the country's third-largest economy. In the same year, San Francisco proper had a GDP of $203.5 billion, and a GDP per capita of $230,829.
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In 2019, San Francisco was the county with the seventh-highest income in the United States, with a per capita income of $139,405. Colloquial nicknames for San Francisco include SF, San Fran, The City, and Frisco. With San Jose, California, it forms the San Jose–San Francisco–Oakland, CA Combined Statistical Area, the fifth most populous combined statistical area in the United States, with 9.6 million residents as of 2019. San Francisco is the 12th-largest metropolitan statistical area in the United States with 4.7 million residents, and the fourth-largest by economic output, with a GDP of $592 billion in 2019. county, behind only four of the five New York City boroughs. city, and the fifth most densely populated U.S. It covers an area of about 46.9 square miles (121 square kilometers), mostly at the north end of the San Francisco Peninsula in the San Francisco Bay Area, making it the second most densely populated large U.S. Located in Northern California, San Francisco is the 17th most populous city in the United States, and the fourth most populous in California, with 873,965 residents as of 2020. San Francisco ( / ˌ s æ n f r ə n ˈ s ɪ s k oʊ/ Spanish for " Saint Francis"), officially the City and County of San Francisco, is a cultural, commercial, and financial center in the U.S.